Akihiro Uchizono

Sendai ENT Clinic, Japan

The drug susceptibility was retrospectively examined for the so-called three major bacterial species (Streptococcus pneumoniae,

Haemophilus influenzae, and Moraxella catarrhalis). Isolates were identified in otorrhea, myringotomy fluid, nasal discharge, pharyngeal

specimens, etc., taken from otorhinolaryngological patients with acute exacerbations of infectious diseases who visited my clinic over the

past 10 years.

Looking at the susceptibility of the three major strains against aminobenzylpenicillin (ABPC), M. catarrhalis is almost 100% resistant

due to production of ?-lactamase in all strains, and the low susceptibility rate of H. influenzae is increasing gradually from ~70%. In

contrast, the resistance of S. pneumoniae is decreasing.

The susceptibility rate of H. influenzae is increasing not only against ABPC, but also against tosufloxacin (TFLX) and tebipenem

pivoxil (TBPM-PI), which are considered to be highly effective agents. All 81 H. influenzae strains detected in 2020 were CDTR-PI-resistant.

Key words: Haemophilus influenzae, Streptococcus pneumoniae, Moraxella catarrhalis, antimicrobial resistance, annual transition

TBA

2nd International Conference on Otorhinolaryngology Research and Treatment