We conducted a retrospective study to analyze the correlation  of age, gender, subsite, and histopathological factors such as tumour grade, depth of invasion (DOI), lymphovascular invasion(LVI), perineural invasion (PNI), bone invasion, and worst pattern of invasion (WPOI) with cervical lymph node metastasis (LNM), extranodal extension (ENE), lymph node ratio(LNR),  number of positive nodes(+veN) and T stage  in oral squamous cell carcinoma (OSCC). Cases with OSCC of all stages and any designated anatomical subsite of the oral cavity, who reported to Rohilkhand Cancer Institute from the year 2018-2023, and  underwent curative-intent  surgery with or without appropriate adjuvant treatment were included. Various clinic-pathological parameters were recorded, and their correlation with lymph node metastasis, lymph node ratio (LNR),  number of positive nodes (+veN), extranodal extension (ENE), and T stage was analyzed. A total of 301 patients with a mean of 43.94±11.23 years were enrolled in the  study, out of which 86% were males and 14% were females. Tumour grade, DOI, LVI, PNI, medullary bone invasion were found to be predictors of LNM, LNR and +veN, All these histopathological parameters excluding tumor grade had a significant association with ENE as well, and  excluding LVI, all of them  had a significant association with T stage. Thus, it was concluded that histopathological parameters have a major role to play in determining the lymph node status in OSCC patients.

Mansi Dey has done Observership in Head and Neck Surgical Oncology from various reputed hospitals in Delhi, India. She also did Fellowship in Oral Oncology and Reconstructive Surgery from Rohilkhand Medical College and Hospital, Bareilly, Uttar Pradesh India. She has also worked as a Lecturer in the Department of Oral and Maxillofacial Surgery at Maharishi Markandeshwar College of Dental Sciences and Research, Mullana, Ambala, Haryana, India, and has delivered lectures about oral cancer to the MBBS students. Apart from teaching the subject of Oral and Maxillofacial Surgery to BDS students, she has also taught zygomaticomaxillary complex fractures and panfacial trauma to MDS final, year students. Thereafter she did Observership in the Department of Cleft and Craniomaxillofacial Surgery, at GNRC Hospital, Kadambagachi, Barasat, West Bengal, India. Currently she is working "medical Officer, Department of Preventive  Oncology, Mahamana Pandit Madan Mohan Malviya Cancer Centre, Varanasi, Uttar Pradesh, India